Low-dose SoluMatrix® NSAIDs effectively manage pain

Low-dose SoluMatrix® NSAIDs (nonsteroidal anti-inflammatory drugs) are a group of medicines that can be used to manage mild to moderate acute pain and osteoarthritis pain.

NSAIDs by the numbers

NSAIDs are among the most commonly prescribed medications for mild to moderate acute pain and pain associated with osteoarthritis, a common form of arthritis that may lead to stiffness and swelling of the joints.

More than

70 million

visits are made to physicians for pain-related ailments each year in the United States.

Approximately

127 million

NSAID prescriptions were filled in the United States in 2015.

NSAIDs are found

in nearly 550

over-the-counter and prescription medicines.

About

62%

of NSAID prescriptions in 2014 were for women.

Taking NSAIDs? Know your dose!

Although NSAIDs may help reduce pain and inflammation, studies have shown they can lead to serious side effects involving the heart, stomach, and kidneys.

The US Food and Drug Administration (FDA), professional medical organizations, and advocacy groups recognize the importance of using the lowest NSAID dose possible for the shortest time needed for your treatment.

  • Studies have shown that the higher the NSAID dose, the higher the risk of certain serious side effects and may increase with longer use
  • Even short-term NSAID use can lead to serious side effects and may increase with longer use

Iroko provides low-dose SoluMatrix® NSAIDs that align with these recommendations.

Learn more about low-dose SoluMatrix® NSAIDs and why they are an important option for effective pain management:

Potential risks associated with NSAID use

The higher the NSAID dose, the higher the risk of certain serious side effects

Risk of heart problems

Increased NSAID doses may increase:

The risk of heart attack or stroke in people with or without heart disease or risk factors for heart disease

Risk of stomach and GI problems

Increased NSAID doses may increase:

The risk of bleeding, ulcers, and tears (perforations) of the esophagus (the tube leading from the mouth to the stomach), stomach, and intestines

Risk of kidney problems

Increased NSAID doses may increase:

The risk of kidney problems, including kidney failure

The majority of commonly used NSAIDs are prescribed at the highest approved daily dose.

NSAIDs: One medication for many types of pain

Doctors frequently prescribe NSAIDs to treat a wide array of painful and inflammatory conditions in adults. Here are just a few of them.

Osteoarthritis pain

Osteoarthritis, commonly referred to as arthritis or OA, is a progressive joint disease that causes cartilage—the tissue that occupies the space where bones meet—to wear away.

Mild to moderate acute pain

Acute pain is short-term pain that is linked to an injury, surgery, or other trauma to the body. NSAIDs are one of the most frequently used medicines to treat acute pain that is mild to moderate in intensity.

Gout pain

Gout is a painful form of arthritis that is caused by the overproduction of uric acid, a bodily waste product. This excess of uric acid causes needle-like crystals to form in the joints, leading to painful flares, swelling, and stiffness.

Trusted NSAIDs meet forward-thinking technology

The science behind low-dose SoluMatrix® NSAIDs

SoluMatrix Fine Particle Technology is an innovative scientific process that is applied to trusted NSAID molecules. This technology:

  • Creates NSAID drug particles that are approximately 10 to 20 times smaller than their original size
  • Helps drugs dissolve quickly so they can be rapidly absorbed in the body

Iroko developed low-dose SoluMatrix® NSAIDs to align with recommendations from the FDA, medical organizations, and advocacy groups using the lowest NSAID dose possible for the shortest time needed for your treatment.

Particle Chart

Original NSAID particles

SoluMatrix® NSAID particles

See how SoluMatrix Fine Particle Technology reduces the size of drug particles!

SoluMatrix® NSAIDs give patients low-dose treatment options

Iroko developed low-dose SoluMatrix® NSAIDs for patients with osteoarthritis pain and mild to moderate acute pain. SoluMatrix® NSAIDs give patients low-dose treatment options, to align with FDA recommendations on NSAID dosing.

For management of osteoarthritis (OA) pain
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For management of mild to moderate acute pain or osteoarthritis (OA) pain
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For treatment of mild to moderate acute pain in adults
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